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Great question. The cost of drugs in pharmacy is usually down to multiple factors but one main one is whether it is under patent or not. In this case ketamine racemic has been used for more than half a century and is not under any licensing restrictions. However, the S Isomer aka esketamine has a patent and therefore is associated with the development costs from industry which they try to recoup through increased price. One big question here, is that the licensee only got the patent on the molecule as it proved at that time that it was more effective. However, now as more data has come out about its relative efficacy to normal ketamine, is this price still justified?

Hi Samantha, not as of yet, however although ibioagaine is specific for addiction, there might be other psychedelic like treatments which might help however you will need to talk to a psychiatrist… So far the data suggests:

Alcohol Use Disorder (AUD): In a double-blind, placebo-controlled phase 2 trial, patients with severe AUD who received three weekly ketamine infusions reported a significantly greater number of abstinent days at a 6-month follow-up compared to a placebo group. Other studies have shown that ketamine can reduce alcohol cravings and binge drinking behaviors.

Cocaine Use Disorder: Preliminary studies indicate that ketamine may reduce cravings, increase motivation to quit, and decrease self-administration of cocaine. One analysis of electronic health records found that patients receiving ketamine for other reasons had two to four times higher remission rates for cocaine use disorder.

Opioid Use Disorder (OUD): Evidence suggests ketamine can suppress physiological withdrawal symptoms and prolong abstinence from heroin in detoxified individuals. More recent research focuses on its ability to help patients transition onto maintenance medications like buprenorphine by alleviating severe withdrawal symptoms.

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I NEED this. HELP
Melbourne Victoria AU

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