Standard Operating Procedures (SOPs) for controlled drugs in pharmacy practice are essential to ensure the safe and effective management of these medications. These SOPs outline the processes for the receipt, storage, dispensing, record-keeping, and disposal of controlled substances, ensuring compliance with legal and regulatory requirements. They define the roles and responsibilities of pharmacy staff, including those responsible for monitoring and maintaining accurate inventories, as well as the procedures for dealing with discrepancies or theft. Additionally, SOPs typically include guidelines on prescribing, administering, and handling controlled drugs in a way that minimizes the risk of misuse or diversion. Regular audits, staff training, and robust documentation are key components of a pharmacy’s controlled drug SOPs, safeguarding both patient safety and regulatory compliance.