pharmacy flu – Online Prescribing https://onlineprescribing.com Online Prescribing Best Practice Mon, 05 Oct 2020 06:19:50 +0000 en-US hourly 1 https://wordpress.org/?v=6.6.1 https://i0.wp.com/onlineprescribing.com/wp-content/uploads/2022/08/cropped-android-chrome-512x512-1.png?fit=32%2C32&ssl=1 pharmacy flu – Online Prescribing https://onlineprescribing.com 32 32 209681591 Are pharmacists proficient vaccinators? https://onlineprescribing.com/are-pharmacists-proficient-vaccinators/ https://onlineprescribing.com/are-pharmacists-proficient-vaccinators/#respond Mon, 05 Oct 2020 06:19:50 +0000 https://voyagermedical.com/?p=641 Flu has been responsible for the world’s most deadly pandemics having once killed 50 million people in a single wave (Spanish Flu, 1918). The technology to produce flu vaccines at a low cost and at scale, to protect the public only emerged in response to the “avian flu” pandemic which broke out in Hong Kong in 1997. To contain this pandemic, scientists invented new techniques of genetic rearrangement which enabled a vast number of vaccine doses to be produced in a short period by applying recombinant DNA technology to the influenza A/H5N1 virus¹.

In the UK, a couple more seasons with even more intense A(H3N2) activity associated with substantial morbidity followed, culminating in a peak over the turn of the Millenium (See figure 1). In mid-2000, this led to the creation of a universal influenza vaccine programme for those aged 65 years and older². The plan was created in order to reach herd immunity targets set by the World Health Organization (WHO) at 75% of at-risk patients.

Figure 1:Excess Winter Mortality in England and Wales, 2014/15 (Provisional) and 2013/14 (Final) Release

With a limited capacity of doctors resulting in a vaccination rate hovering around 36.7%³, the UK government increased supply capacity by proactively amending to the Medicines Act in late 2000 to allow specific classes of healthcare professionals to supply and administer the vaccine (via Patient Group Direction). Over the next few years, there was a steady increase in vaccine rates until 2005/06, when the majority of healthcare professionals were suitably trained England hit its 75% target. Year on year the UK has been consistently seated at the top of the table relative to all European countries, furthermore, the top 4 countries all offer non-doctor vaccinations.

Pharmacist vaccine rate in UK.

Now amid the COVID-19 pandemic, it is estimated that the level of flu vaccines required by the public will triple⁴. The beginning of this has already been shown in the UK which started its flu vaccination season last month. Community pharmacists have already vaccinated more than 650,000 NHS patients in the first four weeks, which is four times average rates from 2018-19⁵.

So why have pharmacy-based flu vaccines proven to be so successful?

One key factor is Pharmacists have consistently proven clinical excellence, ease of use and availability around the world. One of the most substantial pieces of evidence comes from a peer-reviewed meta-analysis from the College of Pharmacy Canada which reviewed thirty-six studies assessing the role of pharmacists in immunization. It is noted that “increased vaccination rates for influenza vaccines were observed with the addition of pharmacists as immunizers” and concludes that:

Pharmacists should be involved with immunization in whatever ways their legislation allows and however they are competent and comfortable. Those pharmacists without legislative authority or who are not comfortable injecting can play an important role in providing immunization education and facilitating immunization, as these roles have also been shown in this systematic review and meta-analysis to increase vaccine coverage.

Canadian Pharmacists Journal, 2018⁶

In fact, the success of pharmacist-led influenza clinics has led to the UK government to consult on the possibility that pharmacy technicians will be able to administer the vaccine…⁷

An expanded workforce eligible for administering the flu vaccine may be required, given the recent announcement of an expanded flu vaccination programme this winter. Millions more could receive the flu vaccine than received it last year, so there is a need to ensure the workforce comprises enough people to deliver these additional vaccinations.

Department of Health & Social Care⁸

So what’s next for pharmacists?

As convenient healthcare demand sores and pharmacists competence is no longer questioned, where next? The key to these new capabilities is clinical governance, to make ensure new services are contained within a framework to avoid medico-legal complications. On top of this data collection is needed to prove to health commissioners and the public the safety and efficacy of the pharmacist workforce. Voyager medical provides such a service via its hubnet.io platform.

References

  1. History and evolution of influenza control through vaccination: from the first monovalent vaccine to universal vaccines. Journal of preventive medicine and hygiene. Published Sep 2016, accessed Oct 2020.
  2. Uptake and effectiveness of influenza vaccine in those aged 65 years and older in the United Kingdom, influenza seasons 2010/11 to 2016/17. Journal of preventive medicine and hygiene. doi: 10.2807/1560-7917.ES.2018.23.39.1800092. Published Sep 2018, accessed Oct 2020.
  3. Influenza vaccine uptake and distribution in England and Wales using data from the General Practice Research Database, 1989/90–2003/04. Journal of Public Health. Published October 2005, accessed Oct 2020.
  4. Community pharmacists vaccinated more than 650,000 NHS patients in the first four weeks of the flu vaccination service. Pharmaceutical Journal, published Oct 2020, accessed Oct 2020.
  5. Influenza vaccine data 2018-19. Pharmaceutical Services Negotiating Committee. Published Sep 2019, accessed Oct 2020.
  6. Canadian Pharmacists Journal [doi 10.1177_1715163518783000] Isenor, Jennifer E.; Bowles, Susan K. — Evidence for pharmacist vaccination. Published Jun 2018, accessed Oct 2020.
  7. Pharmaceutical Journal: Government consults on allowing pharmacy technicians to administer COVID-19 and flu vaccines. Published 28 Aug 2020, accessed Oct 2020.
  8. Changes to Human Medicine Regulations to support the rollout of COVID-19 vaccines: Department of Health & Social Care. Published 28 Aug 2020, accessed Oct 2020.

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Hong Kong Flu 2020? https://onlineprescribing.com/is-hong-kong-the-next-wuhan/ https://onlineprescribing.com/is-hong-kong-the-next-wuhan/#respond Sun, 27 Sep 2020 23:58:24 +0000 https://voyagermedical.com/?p=603 With second and third waves of the COVID-19 pandemic in full bloom, we look at what new pandemic might lie just over the horizon.

Can 2020 get any worse?

The planet has experienced far worse pandemics than COVID-19. Other than the Black Death and European plagues, where epidemiological data is understandably spotty; Russian, Spanish, Asian and Hong Kong Flu have all ranked in the top 5 most deadly, each accounting for over a million deaths.

The Hong Kong Flu Pandemic of 1968 was the fourth worst in recorded history.¹

Of all of these, the Hong Kong flu pandemic which, scourged South Asia in 1968, killing over 1 million people is probably the least well known. Over half a century and three more flu epidemics later, Hong Kong is reknowned³’⁴’⁵’⁶ as the global epicentre of new strains of human and avian influenza viruses.

Europe seems to have learnt from its 1918 lesson. Since 2010, the EU has instigated a 75% vaccine target of at-risk patients, utilising a more comprehensive range of healthcare professionals to reach the target. Hong Kong seems behind the curve, relying on doctors and nurses under supervision, vaccination rates have stagnated at around 29%², with at-risk patients aged 16-64 at merely 13.9%¹⁰. These figures in comparison to other high-income, densely populated areas, is staggeringly low.

With climate experts predicting higher temperatures than ever this year, epidemiological experts say Influenza Type A which accounts for 80% of all influenza hospital admissions in Hong Kong will be on the rise⁶. So how can Hong Kong take a proactive approach and prevent yet another pandemic?

The threat of pandemic should not be minimised, nor should governments be lulled into a false sense of security.

K.F. Shortridge, The next influenza pandemic,University of Hong Kong, 2003³

Inaccessible prophylaxis.

Patient vaccine accessibility has been identified as a critical factor⁴ in causing low levels of flu vaccine uptake in Hong Kong. It has been shown that over 50% of at-risk patients do not know where they can access the influenza vaccine, and those that know where to get the vaccine nearly 40% would have financial difficulties to access the vaccine⁷. One major study⁸ indicates that although public clinics offered free flu vaccinations to the chronically ill patients, some participants believed that time inaccessibility of these clinics was a problem for them, especially for those who had to work. As one participant remarked:

“I know I can receive a free flu vaccine in public clinics, but I need to work for the entire day, and the service hours of the public clinics just cannot match with my work schedule. It’s silly to take a leave [from my work] to do the vaccine.”

Financially prohibitive.

Although the Hong Kong government provides free influenza immunisations to at-risk people, the cost of vaccination due to private doctor charges is still a dissincentive to at-risk patients⁸. One patient remarked:

“I do not have time to go to public clinics just for the vaccination, since I need to work. The only option for me will be private doctors, but I have to pay. I have no motivation to pay for an optional vaccine which seems not to be safe. It’s not worth paying, since I need to run the risk.”

Vaccine cost and availability are the main factors prohibiting the most vulnerable in Hong Kong from accessing a low-cost vaccine which has been proven to massively reduce public health spend. Furthermore, with a new COVID vaccine on the horizon, the Hong Kong government needs to ask itself a question which many countries have already answered. How can the public access a cohort of readily accessible healthcare professionals who are on every high street of the special administrative area to administer more vaccines?

Allow other healthcare professionals to administer vaccines.

According to the FIP, which in 2016 surveyed 44 countries, reported that there are now only 24 countries which do not allow non-doctors to vaccinate patients. From all respondents, 71% (32 countries and territories) reported some level of engagement in support and advocacy activities connected with expanding immunisation service provision.

FIP 2016 survey of countries which allow other healthcare profesisonals to vaccinate.

The data above shows that the special administrative area of Hong Kong seems to sit alongside countries such as Paraguay, Ukraine and India in not allowing pharmacist to vaccinate patients. There are many reasons for this, one is that current legislation does not define the roles and responsibility for pharmacists in this area and that there was limited acceptance and support from other healthcare professionals.

So what are the rate limiting steps to pharmacist vaccinators in Hong Kong?

All occupations are protective of the financial rewards which are specific to their professions and doctors are no exception. The Medical profession’s strongest non financial arguement is also correct, to an extent; healthcare needs to provide patients with only the best care, however, doctors no long hold this as a monopoly. Best practice has been proven amongst pharmacists for almost a decade.

Are pharmacists competent enough?

The largest systematic review and meta-analysis to date¹², included of thirty-six studies was conducted by Professor Jennifer Isenor at Dalhousie University Canada in 2016. The study shows conclusively that pharmacists vaccine immunisation standards were on par with their doctor colleagues and their expanded role led to a increased uptake of immunisations across the board.

Is it worth it?

Epidemiological studies show consistently a relationship between the presence of influenza virus and increased mortality rates, rates of hospital admissions, and health services utilisation. The greatest burden of illness from influenza occurs in the elderly who are at increased risk of death and other serious complications related to influenza. By training healthcare professionals to international best practice and allowing them to admnister vaccines we estimate that over $10 millon HKD can be saved annually.

Is it too late?

It is not too late to act, the influenza season in Hong Kong starts in November, its been said that to get ready, vaccines must be administered at least two weeks before⁷. As a minimum we recommend the Hong Kong government:

  1. To update their “Preparedness plan” from 2014 which should detail out what if anything can be done this year to mitigate potential increased risks⁹.
  2. Adopt proven, best practice training protocols and encourage the private sector to create a “reserve” of health professionals that can potentially handle the increase influenza vaccine demand and bolster potential capacity when a COVID-19 vaccine arrives.

References

¹Sino Biological, Hong Kong Flu (1968 Influenza Pandemic).

²Hong Kong third wave: with Covid-19 set to meet winter flu, let nurses and pharmacists call the shots. South China Morning Post, published, 25 Sep, 2020.

³The next influenza pandemic: lessons from Hong Kong. K.F. Shortridge, J.S.M. Peiris and Y. Guan, Journal of Applied Microbiology, 94, 70S–79S, Department of Microbiology, The University of Hong Kong, Hong Kong SAR, China. Published in 2003.

⁴An influenza epicentre? Shortridge KF, Stuart-Harris CH. Lancet;(ii):832-813. Published in 1982

⁵Excess Hospital Admissions for Pneumonia, Chronic Obstructive Pulmonary Disease, and Heart Failure During Influenza Seasons in Hong Kong. Journal of Medical Virology 73:617–623. Published in 2004.

⁶Seasonal Influenza Activity in Hong Kong and its Association With Meteorological Variations, Journal of Medical Virology 81:1797–1806, Paul K.S. Chan,1,2* H.Y. Mok et al. Published in 2009.

⁷Cross-sectional and longitudinal factors predicting influenza vaccination in Hong Kong Chinese elderly aged 65 and above, Paul K.S. Chan et al, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Journal of Medical Virology 81:1797–1806. Published in 2006.

⁸The perceptions of and disincentives for receiving influenza A (H1N1) vaccines among chronic renal disease patients in Hong Kong. Judy Yuen-Man Siu PhD MPhil BSSc Centre for Health Behaviours Research, School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China. Accepted for publication 12 June 2011

⁹Preparedness for Influenza Pandemic in Hong Kong Nursing Units. Agnes Tiwari, Marie Tarrant, Kwan Hok Yuen, et al. Journal of Nursing Scholarship., 2006; 38:4, 308-313. SIGMA THETA TAU INTERNATIONAL. Published in 2006.

¹⁰Seasonal influenza vaccine uptake among Chinese in Hong Kong: barriers, enablers and vaccination rates, Kai Sing Sun. Journal of Human Vaccines & Immunotherapeutics Volume 16, 2020

¹¹An overview of current pharmacy impact on immunisation. International Pharmaceutical Federation (FIP). Ian Bates at al. Published in 2016.

¹²Impact of pharmacists as immunizers on vaccination rates: A systematic review and meta-analysis, Vaccine 34(47)Dalhousie University Halifax, NS. Published: October 2016

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